− | Fomites may assist the transmission of the virus and the disease can be '''spread both horizontally and vertically''', resulting in '''clinical and subclinical infections, respectively''' and the latter being of particular '''importance''' to '''intensive breeding populations'''. The age of the bird has a marked effect on the development of clinical signs.'''Chicks hatching''' from infected layers of naive flocks (vertical transmission)'''show clinical signs after 10-14 days of age''' over a '''period of 3 to 6 weeks. After which the breeder layers develop sufficient CAV antibodies to stop the transmission of the virus to the egg. '''Mortality peaks''' during the '''third week of life''' around 5 to 10% but can be as high as 60%. Whereas older chicks greater than 14 days old that become infected with CAV do not exhibit clinical signs. | + | Fomites may assist the transmission of the virus and the disease can be spread both '''horizontally''' and '''vertically''', resulting in '''clinical''' and '''subclinical infections''', respectively and the latter being of particular importance to intensive breeding populations. The '''age''' of the bird has a marked effect on the '''development of clinical signs'''.'''Chicks hatching''' from infected layers of naive flocks (vertical transmission)'''show clinical signs after 10-14 days of age''' over a '''period of 3 to 6 weeks'''. After which the breeder layers develop sufficient CAV antibodies to stop the transmission of the virus to the egg. '''Mortality peaks''' during the '''third week of life''' around 5 to 10% but can be as high as 60%. Whereas '''older chicks''' greater than 14 days old that become infected with CAV '''do not exhibit clinical signs'''. |