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→Clinical Signs
Sequelae of hyperparathyroidism include fibrous osteodystrophy and
Sequelae of hyperparathyroidism include fibrous osteodystrophy and
Osteodystrophy is the [[Bone - Anatomy & Physiology#Cells|osteoclastic resorption]] of bone and replacement by weaker fibrous tissue. When this occurs in the long bones it causes shifting lameness and weakened bones that are prone to [[Fractures|fracture]]. Compression fractures may also occur spontaneously and if this occurs in the vertebrae, nerve dysfunction results.<ref>Merck Veterinary Manual, '''Metabolic Osteodystrophies: Fibrous Osteodystrophy: Primary Hyperparathyroidism''', accessed online 25/07/2011 at http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/90313.htm</ref>
Osteodystrophy is the [[Bones - Anatomy & Physiology#Osteoclasts|osteoclastic resorption]] of bone and replacement by weaker fibrous tissue. When this occurs in the long bones it causes shifting lameness and weakened bones that are prone to [[Fractures|fracture]]. Compression fractures may also occur spontaneously and if this occurs in the vertebrae, nerve dysfunction results.<ref>Merck Veterinary Manual, '''Metabolic Osteodystrophies: Fibrous Osteodystrophy: Primary Hyperparathyroidism''', accessed online 25/07/2011 at http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/90313.htm</ref>
Fibrous osteodystrophy in the flat bones of the skull and face causes facial hyperostosis. This is seen in Bran disease or grain overload in horses and also in dogs with primary hyperparathyroidism. The face and head become grossly disfigured by excessive amounts of fibrous tissue laid down in an attempt to consolidate the weakened lamellar bone. In advanced cases, the mandible may become pliant and teeth may loosen, hence the colloquial name, “rubber jaw”. This may interfere with mastication and cause pain, dysphagia and consequent weight loss.
Fibrous osteodystrophy in the flat bones of the skull and face causes facial hyperostosis. This is seen in Bran disease or grain overload in horses and also in dogs with primary hyperparathyroidism. The face and head become grossly disfigured by excessive amounts of fibrous tissue laid down in an attempt to consolidate the weakened lamellar bone. In advanced cases, the mandible may become pliant and teeth may loosen, hence the colloquial name, “rubber jaw”. This may interfere with mastication and cause pain, dysphagia and consequent weight loss.