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==Actions==
==Actions==
Alpha-2 agonists have a wide range of actions, due to the presence of alpha-2 receptors throughout the body. The actions most useful pharmacologically are '''sedation''', '''anxiolysis''' and '''analgesia'''. The drugs also have a huge '''anaesthetic sparing effect''', reducing MAC by 50-95%. They also give '''muscle relaxation'''.
Alpha-2 agonists have a wide range of actions, due to the presence of alpha-2 receptors throughout the body. The most useful pharmacological actions are '''sedation''', '''anxiolysis''' and '''analgesia'''. The drugs also have a huge '''anaesthetic sparing effect''', reducing MAC by 50-95%. They also give '''muscle relaxation'''.
Other systems affected by alpha-2 agonists include:
Other systems affected by alpha-2 agonists include: