Changes

*The spindle cells have granular, evenly distributed chromatin and the nuclei contain one to several small but distinct nucleoli.  

*The spindle cells have granular, evenly distributed chromatin and the nuclei contain one to several small but distinct nucleoli.  

*The cytoplasm is wispy and often has bipolar extensions.

*The cytoplasm is wispy and often has bipolar extensions.

|l1=

|l1=Spindle Cell Tumours#Diagnosis

|q2=What is your interpretation of these findings?

|q2=What is your interpretation of these findings?

|a2=

|a2=

The cytological features are consistent with moderate to marked pyogranulomatous inflammation with spindle cell proliferation, most likely fibroplasia.

The cytological features are consistent with moderate to marked pyogranulomatous inflammation with spindle cell proliferation, most likely fibroplasia.

|l2=

|l2=Spindle Cell Tumours

|q3=What comments do you have regarding these findings?

|q3=What comments do you have regarding these findings?

|a3=

|a3=

However, in some cases, spindle cell proliferations may be difficult to differentiate and it may be difficult or impossible to separate fibroplasia from an actively growing benign tumour or a malignant one. <br><br>

However, in some cases, spindle cell proliferations may be difficult to differentiate and it may be difficult or impossible to separate fibroplasia from an actively growing benign tumour or a malignant one. <br><br>

Cellularity, degree of atypia and other concurrent features all have to be considered. In some cases, cytological evaluation can help separate these conditions with a high degree of confidence.<br><br>

Cellularity, degree of atypia and other concurrent features all have to be considered. In some cases, cytological evaluation can help separate these conditions with a high degree of confidence.<br><br>

In others the differential diagnoses cannot be differentiated on the basis of cytology alone and a biopsy will be needed to determine the definitive diagnosis.

In others the differential diagnoses cannot be differentiated on the basis of cytology alone and a biopsy will be needed to determine the definitive diagnosis.

|l3=

|l3=Spindle Cell Tumours

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