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, 15:31, 9 August 2011
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'''A 7-month-old DSH cat is presented with a 2-month history of waxing and waning inappetence, lethargy, and some weight loss. The owner has noticed that both of the eyes look abnormal.'''
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<FlashCard questions="3">
|q1=What abnormalities are visible?
|a1=
There is obvious hyphaema (blood in the anterior chamber) which has clotted, suggesting a high fibrin content. The remaining view of the aqueous chamber is slightly hazy due to aqueous flare. The iris blood vessels are very prominent suggestive of an intense vasculitis. A focal deposit is visible on the anterior lens capsule and is likely to be a persistent pupillary membrane. The pupil has slightly irregular margins.
|l1=
|q2=What is the likely diagnosis?
|a2=
Anterior uveitis (inflammation of the iris and/or ciliary body) with hyphaema.
|l2=
|q3=What are the possible causes of this condition?
|a3=
Differential diagnoses include:
*Infectious causes, e.g. FIP, FeLV, FIV, Toxoplasma gondii, and systemic mycoses (e.g. histoplasmosis, blastomycoses, cryptococcosis). Recently, FHV and Bartonella henselae have been implicated as possible causes of uveitis.
*Idiopathic uveitis.
*Disseminated neoplasia, especially lymphoma.
*Autoimmune disease.
*Blunt and penetrating trauma to the eye.
FIP was diagnosed in this case. The cat had very high serum globulin levels (69 g/l [6.9 g/dl]), predominantly comprising gamma globulins on serum protein electrophoresis. Haematology revealed a mild anaemia, and lymphopenia.
|l3=
</FlashCard>
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