Changes

Clinical signs are non specific with many other differentials. Nasal, conjunctival, or oropharyngeal swabs can be taken for virus isolation. Cytology of affected cells may demonstrate  pyknosis (an irreversible condensation of chromatin in the cell nucleus undergoing necrosis or apoptosis) - feline herpes causes cellular swelling and syncytia formation.

Clinical signs are non specific with many other differentials. Nasal, conjunctival, or oropharyngeal swabs can be taken for virus isolation. Cytology of affected cells may demonstrate  pyknosis (an irreversible condensation of chromatin in the cell nucleus undergoing necrosis or apoptosis) - feline herpes causes cellular swelling and syncytia formation.

===Control===

==Control==

*Virulent isolate outbreak: quarantine and restrict movement of in contact animals.

*Virulent isolate outbreak: quarantine and restrict movement of in contact animals.

*Prevention: Live or dead [[Vaccines|vaccines]] are available that contain broadly cross-reactive strains. [[Vaccines#Cat_Vaccinations|Vaccination]] is often given in combination with feline herpes and panleukopenia virus immunization.

*Prevention: Live or dead [[Vaccines|vaccines]] are available that contain broadly cross-reactive strains. [[Vaccines#Cat_Vaccinations|Vaccination]] is often given in combination with feline herpes and panleukopenia virus immunization.