without approximately 0.2 U/kg soluble insulin to cause cellular uptake of potassium. Careful monitoring of response (potassium, glucose, and acid–base status) is required. Severe acidosis (pH <7.15) requires bicarbonate therapy using 1–2 mmol or mEq per | without approximately 0.2 U/kg soluble insulin to cause cellular uptake of potassium. Careful monitoring of response (potassium, glucose, and acid–base status) is required. Severe acidosis (pH <7.15) requires bicarbonate therapy using 1–2 mmol or mEq per |