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, 18:48, 10 August 2011
{{Template:Manson Keeble Meredith}}
[[Image:Rabbit Medicine 11.jpg|centre|500px]]
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'''A gram-stained histological section from a rabbit’s cerebrum is shown. The animal presented with severe head tilt and was collapsed. It was euthanased.'''
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<FlashCard questions="2">
|q1=What is your diagnosis?
|a1=
Encephalitozoonosis.
*The photograph shows gram-positive protozoal parasites within macrophages.
*Encephalitozoon cuniculi is an obligate intracellular protozoal parasite, belonging to the order Microsporidia.
*The parasite infects the host cell and eventually the host cell ruptures, releasing parasitic spores, which go on to infect other cells.
*The life cycle lasts 3–5 weeks.
*Rupture of the host cell causes inflammation and results in clinical signs in the host animal.
|l1=
|q2=How is this disease transmitted?
|a2=
*Transmission occurs orally following ingestion of contaminated tissues, food items or infected urine.
*In pet rabbits the most likely route of infection is via ingestion of spores from urine-contaminated food and water.
*Transplacental infection and infection via the respiratory route following inhalation have also been reported.
|l2=
</FlashCard>
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