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Gerbils (Laboratory) - Pathology (view source)
Revision as of 15:31, 12 August 2011
, 15:31, 12 August 2011no edit summary
==Reproductive System==
==Reproductive System==
===Cystic Ovaries===
Geriatric problems in gerbils commonly include cystic ovaries. Cystic ovaries occur in 50% of geriatric females and can result in decreased fertility.
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Macroscopic pathologic findings will include moderate to large cysts on the surface of the ovaries together with metritis, endometrial hyperplasia and myometrial mineralisation.
==Urinary System==
==Urinary System==
===Lead Toxicity===
===Lead Toxicity===
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Macroscopic lesions may include a shrunken liver which will be darkly pigmented. The kidneys will also be small and pitted. Microscopic findings may include acid-fast inclusions within the proximal collecting ducts, tubules and within hepatocytes.
Macroscopic lesions may include a shrunken liver which will be darkly pigmented. The kidneys will also be small and pitted. Microscopic findings may include acid-fast inclusions within the proximal collecting ducts, tubules and within hepatocytes.
===Glomerulonephritis===
==Respiratory System==
Glomerulonephritis develops with concurrent polyuria and polydipsia together with progressive weight loss.
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Macroscopic pathology will show neoplastic lesions within the kidneys which will be shrunken, fibrotic and pitted.
==Nervous System==
===Aural Cholesteatomas===
Spontaneous aural cholesteatomas occur in 50% of gerbils over the age of two. The tumor displaces the tympanum of the ear into the middle ear. Clinical signs include a head tilt.
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Macroscopic pathologic findings will include compression within the inner and middle ear. There is often secondary infection in the ear which results in some bone necrosis and inner ear destruction.
==Cardiovascular System==
==Cardiovascular System==
===Neoplasia===
===Neoplasia===
Older gerbils often develop spontaneous neoplasms. These most commonly affect the skin, adrenal glands, kidneys, spleen, intestine and the female reproductive tract. The most commonly encounteredt type of neoplasms include leiomyomas, subcutaneous fibrosarcomas, sebaceous gland adenomas, adenocarcinomas, duodenal adenocarcinomas, adrenal adenomas and malignant melanomas.
Older gerbils often develop spontaneous neoplasms. These most commonly affect the skin, adrenal glands, kidneys, spleen, intestine and the female reproductive tract. The most commonly encounteredt type of neoplasms include leiomyomas, subcutaneous fibrosarcomas, sebaceous gland adenomas, adenocarcinomas, duodenal adenocarcinomas, adrenal adenomas and malignant melanomas.
[[Category:Laboratory Animal Pathology]]
[[Category:Laboratory Animal Pathology]]