Changes

It can be '''difficult to differentiate''' between the different forms of spindle cell tumours, and also to distinguish between spindle cell neoplasia and a fibroplastic spindle cell proliferative response.

It can be '''difficult to differentiate''' between the different forms of spindle cell tumours, and also to distinguish between spindle cell neoplasia and a fibroplastic spindle cell proliferative response.

===Connective tissue tumours===

'''Connective tissue tumours'''

[[Fibroma]] and [[Fibrosarcoma]]

:[[Fibroma]] and [[Fibrosarcoma]]

Myxoma and myxosarcoma

:[[Lipoma]] and liposarcoma

===Tumours of fat===

'''Tumours of muscle'''

[[Lipoma]] and liposarcoma

:[[Leiomyoma]] and leiomyosarcoma

===Tumours of muscle===

'''Tumours of the blood vessel endothelium'''

[[Leiomyoma]] and leiomyosarcoma

:[[Haemangioma]] and [[Haemangiosarcoma]]

===Tumours of the blood vessel endothelium===

'''Tumours of the lymphatics'''

[[Haemangioma]] and [[Haemangiosarcoma]]

:Lymphangioma and lymphangiosarcoma

'''Other tumours'''

:[[Haemangiopericytoma]] and [[Peripheral Nerve Tumours|Schwannoma]]

 

===Other tumours===

[[Haemangiopericytoma]] and [[Peripheral Nerve Tumours|Schwannoma]]

==Diagnosis==

==Diagnosis==

Generally spindle cell tumours '''do not exfoliate well''', although exception exist.

Generally spindle cell tumours '''do not exfoliate well''', although exceptions exist.

On '''cytological examination''': cells are individual rather than adherent, fusiform, and with indistinct cell borders. Nuclei are often fusiform as well and cytoplasmic tails may fade into the background. It may be possible to determine the tissue of origin if there is evidence of collagen, cartilage, bone, fat or myxomatous material formation by the tumour cells.

On '''cytological examination''': cells are individual rather than adherent, fusiform, and with indistinct cell borders. Nuclei are often fusiform as well and cytoplasmic tails may fade into the background. It may be possible to determine the tissue of origin if there is evidence of collagen, cartilage, bone, fat or myxomatous material formation by the tumour cells.

A '''biopsy and histopathology''' are usually necessary to confirm the diagnosis.

A '''biopsy and histopathology''' are usually necessary to confirm the diagnosis.

==Treatment and prognosis==

==Treatment and Prognosis==

'''Benign forms''' are usually well circumscribed and can be surgically removed with an '''excellent prognosis'''.

'''Benign forms''' are usually well circumscribed and can be surgically removed with an '''excellent prognosis'''.

Freeman, K. (2007) '''Self-assessment colour review of Veterinary Cytology''' ''Manson Publishing''

Freeman, K. (2007) '''Self-assessment colour review of Veterinary Cytology''' ''Manson Publishing''

[[Category:To Do - Helen]]

 

[[Category:To Do - Review]]

[[Category:Neoplasia]]

[[Category:Expert Review]]