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These tumours are seen mostly in '''younger dogs''', and the incidence drops drastically after 3 years of age. There are no apparent breed or sex predilections.
These tumours are seen mostly in '''younger dogs''', and the incidence drops drastically after 3 years of age. There are no apparent breed or sex predilections.
==Clinical signs==
==Clinical Signs==
Histiocytomas generally arise on the '''head, ears and limbs''' of dogs, and appear as rapidly-growing, '''erythematous, dome-shaped nodules less than 2.5cm in diameter'''. They are usually solitary, though multiple lesions can appear in a short period of time.
Histiocytomas generally arise on the '''head, ears and limbs''' of dogs, and appear as rapidly-growing, '''erythematous, dome-shaped nodules less than 2.5cm in diameter'''. They are usually solitary, though multiple lesions can appear in a short period of time.
'''Alopecia and ulceration''' are common.
'''Alopecia and ulceration''' are common.
'''Lymphadenopathy''' can occur due to migration of histiocytoma cells to the draining lymph nodes.
'''[[Lymphadenopathy]]''' can occur due to migration of histiocytoma cells to the draining lymph nodes.
==Diagnosis==
==Diagnosis==
A cytology sample should be taken by '''fine needle aspiration'''.
A cytology sample should be taken by '''fine needle aspiration'''. A cytological diagnosis is not always easy to make for these tumours, and they can be confused with granulomatous inflammation, [[Mast Cell Tumour|mast cell tumors]], plasmacytomas, and [[Lymphosarcoma|cutaneous lymphosarcomas]].
A cytological diagnosis is not always easy to make for these tumours, and they can be confused with granulomatous inflammation, mast cell tumors, plasmacytomas, and cutaneous lymphosarcomas.
On '''cytology''': the cells appear round, with moderate anisocytosis and anisokaryosis. Nucleoli may vary from inconspicuous to prominent.
On '''cytology''': the cells appear round, with moderate anisocytosis and anisokaryosis. Nucleoli may vary from inconspicuous to prominent.
Gross, T. (2005) '''Skin diseases of the dog and cat''' ''Wiley-Blackwell''
Gross, T. (2005) '''Skin diseases of the dog and cat''' ''Wiley-Blackwell''
[[Category:To Do - Review]]
{{review}}
[[Category:Neoplasia]]
[[Category:Dermatological Diseases - Dog]]
[[Category:Expert Review - Small Animal]]