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Reproductive System Development (view source)
Revision as of 13:18, 22 August 2011
, 13:18, 22 August 2011→Bipotential Gonadal Phase
===Bipotential Gonadal Phase===
===Bipotential Gonadal Phase===
This phase represents the development of gonadal precursor tissue near the kidneys from the genital ridges.
This phase represents the development of gonadal precursor tissue near the kidneys from the genital ridges. The initial development of the gonads is the same between males and females at this stage. The initial structures present at this stage are the early developmental stages of the rectum, the '''metanephros''' which are the early kidneys, the '''mesonephros''' which are tissues associated with the early gonads, the '''paramesonephric duct''' which runs between the mesonephros and the rectum/urogenital sinus and the '''mesonephric duct''' which connects the mesonephros with the metanephros.
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The paramesonephric ducts then decreases in length towards the urogenital tract and the early developmental gonads begin to enlarge. By the end of this early developmental stage the mesonephros becomes a remnant and eventually becomes the future efferent ducts. In the female the '''paramesonephric duct''' ultimately becomes the female urinogenital tract, but for the next developmental stage it becomes the '''Mullerian duct'''. The '''mesonephric ducts''' in the male eventually become the future epididymis but for the next developmental stage becomes the '''Wolfian duct'''.
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There are a number of genes involved in this stage of bipotential gonadal determination; '''WT-1''', '''SF-1''', '''Lim-1''' and '''EMx-2'''. The development of either the Mullerian duct is caused by the genes '''SRY''', '''SOX-9''', '''DMRT''' and '''1/2'''. The Wolfian ducts
===Pimary Sexual Differentiation Phase===
===Pimary Sexual Differentiation Phase===