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===Murine Parainfluenza - 1 (Sendai virus)===
===Murine Parainfluenza - 1 (Sendai virus)===
*Endemic in many mouse colonies
*Most mice show no symptoms due to maternal antibodies
*But minor respiratory lesions may invalidate carcinogenic or toxicological studies
*Immunological studies also confused due to virus activating NK cells via high circulating IF 3-4 days post-infection
*Controlled achieved by:
**Purchasing specific pathogen free (SPF) mice
**Kill whole colony in an outbreak -> disinfection -> formalin fumigation