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'''This 12-year-old, neutered female cat presented with a plantigrade posture and a prolonged history of polyuria/polydipsia.'''

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<FlashCard questions="2">
|q1=What is the most likely diagnosis?
|a1=
Diabetes mellitus.

The plantigrade posture where the cat walks with its hocks touching the ground is a not uncommon presenting feature of diabetes mellitus in the cat and presumably results from a peripheral neuropathy.

Such a diagnosis is supported by the history of polyuria/polydipsia.
|l1=
|q2=How would you confirm the diagnosis?
|a2=
By demonstrating a fasting hyperglycaemia and glucosuria.

Persistence of these findings on serial sampling is important to eliminate other possible causes of glucosuria and hyperglycaemia, particularly stress-induced hyperglycaemia which commonly occurs in cats.

If ketones are also present in the urine, a diagnosis of diabetes mellitus is confirmed.

Other non-specific but supportive abnormalities include hypercholesterolaemia, increased activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP), hyperbilirubinaemia and a stress leucogram with a mild nonregenerative anaemia.
|l2=
</FlashCard>

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