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==Diagnosis==
 
==Diagnosis==
The aetiology of neurological disease can be suggested by signalment. [[Inclusion Body Disease|Inclusion body disease (IBD)]] is almost always seen in [[Boidae]]. [[Ophidian Paramyxovirus|Ophidian paramyxovirus]] (OPMV) occurs principally in [[Viperidae]]. Hypothiaminosis is common in fish-eating snakes such as [[Garter Snake|garter snakes]].  Disorientation and sluggishness may be attributed to a wide variety of causes but may be simply caused by an inappropriate environmental temperature.  [[Snake Physical Examination|Physical examination]] may rule out cases of trauma.  The use of diagnostic aids may identify the cause: [[Lizard and Snake Imaging|radiography]] may reveal fractures, [[Lizard and Snake Haematology|haematology]] may indicate an infectious cause, and serology may identify [[Ophidian Paramyxovirus|OPMV]]. Response to thiamine is diagnostic for [[Snake Hypothiaminosis|hypothiaminosis]]. However sometimes the aetiology is only found upon [[Snake Necropsy|necropsy]]. Perivascular cuffing in CNS issue may be associated with viral infections.
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The aetiology of neurological disease can be suggested by signalment. [[Inclusion Body Disease|Inclusion body disease (IBD)]] is almost always seen in [[Boidae]]. [[Ophidian Paramyxovirus|Ophidian paramyxovirus]] (OPMV) occurs principally in [[Viperidae]]. Hypothiaminosis is common in fish-eating snakes such as [[Garter Snake|garter snakes]].  Disorientation and sluggishness may be attributed to a wide variety of causes but may be simply caused by an inappropriate environmental temperature.  Stargazing in very suggestive of meningoencephalitis.  [[Snake Physical Examination|Physical examination]] may rule out cases of trauma.  The use of diagnostic aids may identify the cause: [[Lizard and Snake Imaging|radiography]] may reveal fractures, [[Lizard and Snake Haematology|haematology]] may indicate an infectious cause, and serology may identify [[Ophidian Paramyxovirus|OPMV]]. Response to thiamine is diagnostic for [[Snake Hypothiaminosis|hypothiaminosis]]. However sometimes the aetiology is only found upon [[Snake Necropsy|necropsy]]. Perivascular cuffing in CNS issue may be associated with viral infections.
    
==Causes of neurological disease==
 
==Causes of neurological disease==
 
There are many causes of neurological disease in snakes. Here’s a brief overview.
 
There are many causes of neurological disease in snakes. Here’s a brief overview.
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*'''Viral''' - Two viral diseases have been reported to cause neurological problems in snakes – [[Inclusion Body Disease]] and [[Ophidian Paramyxovirus|OMPV]]. [[Ophidian Paramyxovirus|OPMV]] is primarily associated with [[Snake Respiratory Disease|respiratory pathology]] but can be associated with CNS disease. The clinical significance of infection with western equine encephalitis and Venezuelan equine encephalitis is unknown.
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*'''Viral''' - Several viral infections have been reported to cause neurological problems in snakes – including [[Inclusion Body Disease]], [[Ophidian Paramyxovirus|OMPV]], reovirus and lentivirus infections. [[Ophidian Paramyxovirus|OPMV]] is primarily associated with [[Snake Respiratory Disease|respiratory pathology]] but can be associated with CNS disease. The clinical significance of infection with western equine encephalitis and Venezuelan equine encephalitis is unknown.
    
*'''Bacterial''' - Bacterial infections, including Staphylococcus aureus and mycobacteria, have been reported to cause neurological disease and abscesses in the vertebral canal.
 
*'''Bacterial''' - Bacterial infections, including Staphylococcus aureus and mycobacteria, have been reported to cause neurological disease and abscesses in the vertebral canal.
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'''For more information, see''' [[Snake Supportive Care]].
 
'''For more information, see''' [[Snake Supportive Care]].
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==Prognosis==
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If the snake develops severe neurological signs such as ‘star-gazing’ prognosis is generally poor. This is because damage to nervous tissue is irreversible, as this tissue has very poor regenerative qualities.
    
==Prevention==
 
==Prevention==
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'''For further information, see''' [[Snake Feeding and Digestion]] '''and''' [[Snake Housing]].
 
'''For further information, see''' [[Snake Feeding and Digestion]] '''and''' [[Snake Housing]].
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{{Learning
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|flashcards = [[Reptiles and Amphibians Q&A 10]]
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}}
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==Literature Search==
 
==Literature Search==
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[http://www.cabi.org/cabdirect/FullTextPDF/2009/20093118385.pdf '''Neurologic examination in reptiles - Part II: Localizing neurologic dysfunction.''' Bennett, R. A.; The North American Veterinary Conference, Gainesville, USA, Small animal and exotics. Proceedings of the North American Veterinary Conference, Orlando, Florida, USA, 17-21 January, 2009, 2009, pp 1768-1769 - '''Full Text Article''']
 
[http://www.cabi.org/cabdirect/FullTextPDF/2009/20093118385.pdf '''Neurologic examination in reptiles - Part II: Localizing neurologic dysfunction.''' Bennett, R. A.; The North American Veterinary Conference, Gainesville, USA, Small animal and exotics. Proceedings of the North American Veterinary Conference, Orlando, Florida, USA, 17-21 January, 2009, 2009, pp 1768-1769 - '''Full Text Article''']
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==References==
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Frye, FL & Williams, DL (1995) '''Self-Assessment Colour Review - Reptiles & Amphibians''' ''Manson''
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[[Category: To Do - Siobhan Brade]]
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[[Category:To Do - Manson review]]
       
[[Category:Snake_Diseases]]
 
[[Category:Snake_Diseases]]
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