Changes

==Clinical Signs==

==Clinical Signs==

Systemic infection is common. However, infection may also become localised in joints and skin in chronic cases. In addition, localised infection of the oviduct may develop resulting in blind layers when the birds grow up.

Systemic infection is common. However, infection may also become localised in joints and skin in chronic cases. In addition, localised infection of the oviduct of young layers can lead to permanent damage to the developing reproductive tract. This will prevent the proper formation or passage of eggs and result in the birds becoming "blind layers" when they grow up.

Disease is then '''multisystemic''' and can comprise of '''greenish [[Diarrhoea|diarrhoea]]''', pyrexia, anorexia, growth retardation, nasal discharge, coughing, restlessness, polydipsia, '''ataxia, hypermetria, weakness, tremors''' and limb swelling. Nervous signs develop when the organism crosses the blood:brain barrier. Conjunctivitis, chemosis, scleral inflammation and ocular discharge sometimes also occur.  In late disease, young birds may suffer from characteristic '''convulsions'''.  

Disease is then '''multisystemic''' and can comprise of '''greenish [[Diarrhoea|diarrhoea]]''', pyrexia, anorexia, growth retardation, nasal discharge, coughing, restlessness, polydipsia, '''ataxia, hypermetria, weakness, tremors''' and limb swelling. Nervous signs develop when the organism crosses the blood:brain barrier. Conjunctivitis, chemosis, scleral inflammation and ocular discharge sometimes also occur.  In late disease, young birds may suffer from characteristic '''convulsions'''.