The use of Vincristine (a drug also used in chemotherapy for neoplasia) has been advocated in cases of thrombocytopaenia as it increases the rate of fragmentation of megakaryocytes and decreases the descruction of platelets by macrophages. A single intravenous dose is usually given. | The use of Vincristine (a drug also used in chemotherapy for neoplasia) has been advocated in cases of thrombocytopaenia as it increases the rate of fragmentation of megakaryocytes and decreases the descruction of platelets by macrophages. A single intravenous dose is usually given. |