Changes

'''Iodide''' is required for the synthesis of thyroid hormones.  

'''Iodide''' is required for the synthesis of thyroid hormones.  

Goitre is the '''most common endocrine disorder''' reported in fish and has been reported in a large number of freshwater, seawater or brackish water, in captive and natural environments.

Goitre is the '''most common endocrine disorder''' reported in fish and has been reported in a large number in freshwater, seawater or brackish water, in captive and natural environments.

'''Iodide deficiency''' leads to a decrease in thyroid hormone production which stimulates an increase in TSH which leads to a growth in size and number of thyrocytes, which appears as a goiter.  

'''Iodide deficiency''' leads to a decrease in thyroid hormone production which stimulates an increase in TSH which leads to a growth in size and number of thyrocytes, which appears as a goiter.  

Sometimes the ability to take up iodide from environmental sources is impaired, for example by '''nitrites'''.

Sometimes the ability to take up iodide from environmental sources is impaired, for example by '''nitrites'''.

Certain '''metabolic byproducts of bacteria''' may also be goitrogenic and account for goitres in fish help in captivity with filter systems relying on bacterial action.

Certain '''metabolic byproducts of bacteria''' may also be goitrogenic and account for goitres in fish held in captivity with filter systems relying on bacterial action.

==Clinical Signs==

==Clinical Signs==

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=References==

==References==

Leatherland, J. (2006) '''Protozoan and Metazoan Infections, Volume 2''' ''CABI''

Leatherland, J. (2006) '''Protozoan and Metazoan Infections, Volume 2''' ''CABI''

Lewbart, G. (1998) '''Self-assessment colour review of Ornamental Fish''' ''Manson Publishing''

Lewbart, G. (1998) '''Self-assessment colour review of Ornamental Fish''' ''Manson Publishing''

[[Category:To Do - Helen]]

 

[[Category:To Do - Review]]

[[Category:Fish Diseases]]

[[Category:Expert Review - Exotics]]