Changes

Diseased fish are usually in normal nutritional condition but may swim sluggishly near the water surface or "hang" listlessly at the wall of the netpen and eventually sink to the bottom.  

Diseased fish are usually in normal nutritional condition but may swim sluggishly near the water surface or "hang" listlessly at the wall of the netpen and eventually sink to the bottom.  

ISA infections eventually cause '''severe anaemia and multi-organ haemorrhage'''. This may be seen as '''pallor, abdominal distension, scale oedema or fluid accumulation''' in the abdomen and musculature. The '''gills '''are often '''pale''' first and most markedly. Fish may develop a “pop-eye” appearance '''(exopthalmos)'''.

ISA infections eventually cause '''severe anaemia and multi-organ haemorrhage'''. This may be seen as '''pallor, abdominal distension, scale oedema or fluid accumulation''' in the abdomen and musculature. The '''gills '''are often '''pale''' first and most markedly. Fish may develop a “pop-eye” appearance '''([[Exopthalmos - Fish|exopthalmos]])'''.

'''Haematocrit values below 10''' are seen in advanced disease, commonly being found <25 and thus leading to multi-organ dysfunction.

'''Haematocrit values below 10''' are seen in advanced disease, commonly being found <25 and thus leading to multi-organ dysfunction.