Changes

*[[Immune_Mediated_Haemolytic_Anaemia|primary immune-mediated haemolytic anaemia]]

*[[Immune_Mediated_Haemolytic_Anaemia|primary immune-mediated haemolytic anaemia]]

*Heinz body haemolytic anaemia (onions, garlic,propofol)

*Heinz body haemolytic anaemia (onions, garlic,propofol)

*other infectious causes such as ''Babesia felis'' and ''Cytauxzoon felis''

*other infectious causes such as ''Babesia felis'' and [[Cytauxzoon#Cytauxzoon_felis|''Cytauxzoon felis'']]

*[[Neoplasia_-_Pathology|neoplasia]]

*[[Neoplasia_-_Pathology|neoplasia]]

==Treatment==

==Treatment==

The treatment of choice is for Mhf infection is doxycycline at 10mg/kg/d for at least two weeks. Only cats who are anaemic and have clinical signs and laboratory results consistent with haemoplasmosis should be treated as the drug does not reliably eliminate the organism<ref name="Sykes"></ref>. For this reason a PCR-positive cat may not become negative despite treatment and therapy cannot be used to ensure blood donor cats are free from infection.

The treatment of choice is for Mhf infection is [[Tetracyclines|doxycycline]] at 10mg/kg/d for at least two weeks. Only cats who are anaemic and have clinical signs and laboratory results consistent with haemoplasmosis should be treated as the drug does not reliably eliminate the organism<ref name="Sykes"></ref>. For this reason a PCR-positive cat may not become negative despite treatment and therapy cannot be used to ensure blood donor cats are free from infection.

[[Fluoroquinolones|Enrofloxacin]] given at 5mg/kg/d is also an effective treatment <ref name="Tasker">Tasker, S, Helps CR, Day MJ et al.(2004) Use of a Taqman PCR to determine the response to ''Mycoplasma haemofelis'' infection to antibiotic treatment. '''JMicrobiol Methods''' 56(1):63-71</ref> but is a second choice due to the risk of acute retinal damage in cats.

[[Fluoroquinolones|Enrofloxacin]] given at 5mg/kg/d is also an effective treatment <ref name="Tasker">Tasker, S, Helps CR, Day MJ et al.(2004) Use of a Taqman PCR to determine the response to ''Mycoplasma haemofelis'' infection to antibiotic treatment. '''JMicrobiol Methods''' 56(1):63-71</ref> but is a second choice due to the risk of acute retinal damage in cats.

Antimicrobial therapy and blood tranfusions should be initiated before PCR results are known, as this may take several days. In cats testing negative for Mhf and failing to respond to therapy, alternative diagnoses should be considered.

Antimicrobial therapy and blood tranfusions should be initiated before PCR results are known, as this may take several days. In cats testing negative for Mhf and failing to respond to therapy, alternative diagnoses should be considered.

The use of glucocorticoids to suppress immune-mediated damage to erythrocytes has been suggested. However, as this treatment may cause reactivation of a latent infection it is recommended that they only be used in cats not responding to doxycycline and/or for whom there is no definitive diagnosis.

The use of [[Steroids|glucocorticoids]] to suppress immune-mediated damage to erythrocytes has been suggested. However, as this treatment may cause reactivation of a latent infection it is recommended that they only be used in cats not responding to doxycycline and/or for whom there is no definitive diagnosis.

==Prognosis==

==Prognosis==