Changes

To then either kill the pathogens or digest the dead cells, '''lysosomes''', which contain a large range of enzymes, fuse with the phagosome to form the '''lysophagosome'''. One example of a process that occurs in these vesicles is oxygen-dependent degradation which utilizes oxygen (O₂^-) and chlorine (Cl*) free-radicals, hydrogen peroxide (OH), and nitric oxide (NO) to degrade the contents within the lysophagosome. The essential enzyme within this process is NADPH oxidase. In humans, the lethal genetic disease chronic granulomatous disease (CGD) is caused by the lack of NADPH oxidase in the phagocytes, with sufferers rarely living past their mid-twenties (with the help of antibiotics) usually succumbing to lung infection.

To then either kill the pathogens or digest the dead cells, '''lysosomes''', which contain a large range of enzymes, fuse with the phagosome to form the '''phagolysosome'''. One example of a process that occurs in these vesicles is oxygen-dependent degradation which utilizes oxygen (O₂^-) and chlorine (Cl*) free-radicals, hydrogen peroxide (OH), and nitric oxide (NO) to degrade the contents within the lysophagosome. The essential enzyme within this process is NADPH oxidase. In humans, the lethal genetic disease chronic granulomatous disease (CGD) is caused by the lack of NADPH oxidase in the phagocytes, with sufferers rarely living past their mid-twenties (with the help of antibiotics) usually succumbing to lung infection.