#* The temperature of the inflamed portion approximates to internal body temperature.
#* The temperature of the inflamed portion approximates to internal body temperature.
# '''Pain''' (dolor)
# '''Pain''' (dolor)
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#*Chemical mediators of pain are released by damaged tissue. in the affected tissue caused by #* Inflammatory exudate puts local pressure on nerve endings.
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#* Chemical mediators of pain are released by damaged tissue.
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#* Inflammatory exudate puts local pressure on nerve endings.
# '''Loss of function'''
# '''Loss of function'''
#* The pain and damage to the tissue result in a reluctance to use the inflamed portion.
#* The pain and damage to the tissue result in a reluctance to use the inflamed portion.
==Causes==
==Causes==
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There are many causes of inflammation. It can happen due to infiltration of microorganisms and helminths (parasites); to trauma; to some mechanical, thermal, and chemical agents; to some immune reactions; to hypersensitivity/ allergy; and to malignant neoplasms. Each of these causes, although exhibiting symptoms that are very similar, have very different mechanisms to starting inflammation. The outcome of inflammation can also vary considerably, with the best outcome being resolved, [[Acute Inflammation|acute inflammation]], with the worst being continuing, [[Chronic Inflammation|chronic inflammation]].