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Major Histocompatability Complexes (view source)
Revision as of 09:02, 16 May 2012
, 09:02, 16 May 2012→Presentation Pathway
*These pathways (endoytotic and secretory) merge to allow interaction between the antigen and MHC II and the invariant chain is digested, leaving a CLIP peptide in the binding groove.
*These pathways (endoytotic and secretory) merge to allow interaction between the antigen and MHC II and the invariant chain is digested, leaving a CLIP peptide in the binding groove.
*Foreign antigen then replaces the CLIP peptide
*Foreign antigen then replaces the CLIP peptide
*The MHC II-antigen complex is then secreted to the cell surface for presentation to [[T_cells#Helper_CD4.2B|CD4+ T-cells]]
*The MHC II-antigen complex is then secreted to the cell surface for presentation to [[T_cells#Helper_CD4.2B|CD4<sup>+</sup> T-cells]]
==Antigen/MHC Interaction==
==Antigen/MHC Interaction==