Changes

===Presentation Pathway===

===Presentation Pathway===

[[File:MHC Class II Presentation.png|thumb|left|200px|MHC Class II Presentation pathway - RJ Francis, RVC, 2012]]

[[File:MHC Class II Presentation.png|thumb|left|200px|MHC Class II Presentation pathway - RJ Francis, RVC, 2012]]

MHC II presents '''exogenous''' (ECF) peptides. Endocytosed antigen interacts with MHC II in the cytoplasm to form a complex:

MHC II presents '''exogenous''' (Extracellular Fluid) peptides. Endocytosed antigen interacts with MHC II in the cytoplasm to form a complex:

*Antigen is endoycotsed from the ECF

*Antigen is endoycotsed from the ECF

*Lysosomes fuse with primary endosomes to digest the antigen to peptides

*Lysosomes fuse with primary endosomes to digest the antigen to peptides