Cell-mediated immunity provides help for macrophages. It includes [[Immunoglobulin G|IgG]] production (through T-helper type II (TH<sub>2</sub>) cell interaction with [[Lymphocytes#B Cells|B cells]]), which improves phagocytosis by opsonisation. Infected [[Macrophages|macrophages]] are rescued by T-helper type I (TH<sub>1</sub>) cells when phagocytosis and digestion mechanisms fail to eliminate the pathogen. | Cell-mediated immunity provides help for macrophages. It includes [[Immunoglobulin G|IgG]] production (through T-helper type II (TH<sub>2</sub>) cell interaction with [[Lymphocytes#B Cells|B cells]]), which improves phagocytosis by opsonisation. Infected [[Macrophages|macrophages]] are rescued by T-helper type I (TH<sub>1</sub>) cells when phagocytosis and digestion mechanisms fail to eliminate the pathogen. |