− | *'''Platelets'''- cytotoxic activity is increased by cytokines such as TNF-alpha and IFN-γ
| + | '''[[Platelets|Platelets]]''' also form part of the innate immune response to parasites. Their main mode of action is the binding and release of granular contents, in particular inflammatory peptides. The cytotoxic activity of plateltes is increased by cytokines such as TNFα and IFNγ. The potential targets include the larval stage of flukes, e.g. ''T. gondii'', ''T. cruzi'' and ''S. Mansoni''. Like other effector cells, platelets express Fc receptors, making them able to perform antibody-dependent cytotoxicity. |