Changes

[[Image:B Cell viral response.jpg|thumb|right|200px|B Cell Immunity to Viruses - B. Catchpole, RVC 2008]]

[[Image:B Cell viral response.jpg|thumb|right|200px|B Cell Immunity to Viruses - B. Catchpole, RVC 2008]]

*Antibodies - these are particularly important in preventing the spread of the virus in the bloodstream

*[[Immunoglobulin|Antibodies]] - these are particularly important in preventing the spread of the virus in the bloodstream

**[[IgA]] production is increased at mucosal surfaces- helps prevent reinfection

**[[IgA]] production is increased at mucosal surfaces- helps prevent reinfection

**Although antibodies that target any viral protein can be produced, only those directed against proteins found in the virion envelope or infected cell membrane will be effective

**Although antibodies that target any viral protein can be produced, only those directed against proteins found in the virion envelope or infected cell membrane will be effective

**When targeting virus-infected cells, they aid antibody-dependent cell-mediated cytotoxicity by NK cells, macrophages and [[Neutrophils|neutrophils]]

**When targeting virus-infected cells, they aid antibody-dependent cell-mediated cytotoxicity by NK cells, macrophages and [[Neutrophils|neutrophils]]

*Complement - although not considered a major factor in defence against viruses, complement is able to damage the virion envelope (virolysis)

*[[Complement]] - although not considered a major factor in defence against viruses, complement is able to damage the virion envelope (virolysis)

**Coupled with antibody, complement is also able to:

**Coupled with antibody, complement is also able to:

***block the virus receptor

***block the virus receptor