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| Also known as: '''''Exudative Cholangitis — Cholangiohepatitis —Suppurative Cholangitis''''' | | Also known as: '''''Exudative Cholangitis — Cholangiohepatitis —Suppurative Cholangitis''''' |
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− | ==Description== | + | ==Introduction== |
| '''Neutrophilic cholangiohepatitis''' is characterised by infiltration of large numbers of [[Neutrophils|neutrophils]] into portal areas of the [[Liver - Anatomy & Physiology|liver]] and into the [[Liver - Anatomy & Physiology #Hepatic Duct Systems|bile ducts]]. It results from ascending bacterial infection from the [[Small Intestine Overview - Anatomy & Physiology|small intestines]]. ''[[Escherichia coli]]'', [[:Category:Staphylococcus species|''Staphylococcus spp.'']], ''[[:Category:Streptococcus species|Streptococcus]] spp.'', ''[[:Category:Clostridium species|Clostridium spp.]]'', ''[[Bacillus species|Bacillus spp.]]'', ''[[:Category:Actinomyces|Actinomyces spp.]]'', ''Bacteroides spp'' and occasionally ''[[Salmonella|Salmonella spp.]]'' have been isolated. Concurrent biliary tract disease are common in cats, especially [[Pancreatitis|pancreatitis]] and [[Inflammatory Bowel Disease|inflammatory bowel disease]]. Other predisposing factors include congenital or acquired abnormalities of the biliary system such as that of anatomic abnormalities of the [[Gall Bladder - Anatomy & Physiology|gall bladder]] or common bile duct, bile duct obstruction caused by inspissated bile, cholelithiasis and cholecystitis. | | '''Neutrophilic cholangiohepatitis''' is characterised by infiltration of large numbers of [[Neutrophils|neutrophils]] into portal areas of the [[Liver - Anatomy & Physiology|liver]] and into the [[Liver - Anatomy & Physiology #Hepatic Duct Systems|bile ducts]]. It results from ascending bacterial infection from the [[Small Intestine Overview - Anatomy & Physiology|small intestines]]. ''[[Escherichia coli]]'', [[:Category:Staphylococcus species|''Staphylococcus spp.'']], ''[[:Category:Streptococcus species|Streptococcus]] spp.'', ''[[:Category:Clostridium species|Clostridium spp.]]'', ''[[Bacillus species|Bacillus spp.]]'', ''[[:Category:Actinomyces|Actinomyces spp.]]'', ''Bacteroides spp'' and occasionally ''[[Salmonella|Salmonella spp.]]'' have been isolated. Concurrent biliary tract disease are common in cats, especially [[Pancreatitis|pancreatitis]] and [[Inflammatory Bowel Disease|inflammatory bowel disease]]. Other predisposing factors include congenital or acquired abnormalities of the biliary system such as that of anatomic abnormalities of the [[Gall Bladder - Anatomy & Physiology|gall bladder]] or common bile duct, bile duct obstruction caused by inspissated bile, cholelithiasis and cholecystitis. |
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| Good prognosis provided the cats are treated early and appropriately. | | Good prognosis provided the cats are treated early and appropriately. |
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− | ==Literature Search==
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| + | |literature search = [http://www.cabdirect.org/search.html?q=title%3A%28Cholangitis%29+AND+title%3A%28Neutrophilic%29 Neutrophilic Cholangitis publications] |
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− | Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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− | [http://www.cabdirect.org/search.html?q=title%3A%28Cholangitis%29+AND+title%3A%28Neutrophilic%29 Neutrophilic Cholangitis publications] | |
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| ==References== | | ==References== |
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| *Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine (Fourth Edition)''' ''Mosby Elsevier''. | | *Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine (Fourth Edition)''' ''Mosby Elsevier''. |
| *Marks, S.L. (2003). '''Update on the Diagnosis and Management of Feline Cholangiohepatitis''' ''Waltham Feline Medicine Symposium''. | | *Marks, S.L. (2003). '''Update on the Diagnosis and Management of Feline Cholangiohepatitis''' ''Waltham Feline Medicine Symposium''. |
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| [[Category:Gall_Bladder_and_Tract_-_Pathology]] | | [[Category:Gall_Bladder_and_Tract_-_Pathology]] |
| [[Category:Expert Review]] | | [[Category:Expert Review]] |