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==Introduction==
==Description==
Colitis X (so-called due to its unknown aetiology) is a peracute and highly fatal disease of horses. Is characterised by severe colitis, sudden watery diarrhoea and death within 24 hours. A number of possible underlying causes have been described, including drug or parasite hypersensitivity, stress and transport. [[Clostridium perfringens type A|''Clostridium perfringens'' Type A]] has been hypothesised to be a cause of Colitis x, and high-protein, low-cellulose diets or antimicrobial treatment may predispose to Clostridial overgrowth. Recently a link has been demonstrated with the current human epidemic strain of ''[[Clostridium difficile]]'' (ribotype 027/toxinotype III) clostridial enterocolitis.
Colitis X (so-called due to its unknown aetiology) is a peracute and highly fatal disease of horses. Is characterised by severe colitis, sudden watery diarrhoea and death within 24 hours. A number of possible underlying causes have been described, including drug or parasite hypersensitivity, stress and transport. [[Clostridium perfringens type A|''Clostridium perfringens'' Type A]] has been hypothesised to be a cause of Colitis x, and high-protein, low-cellulose diets or antimicrobial treatment may predispose to Clostridial overgrowth. Recently a link has been demonstrated with the current human epidemic strain of ''[[Clostridium difficile]]'' (ribotype 027/toxinotype III) clostridial enterocolitis.
The prognosis is usually poor, with a mortality rate approaching 90-100%. This may be lower for horses receiving intensive treatment.
The prognosis is usually poor, with a mortality rate approaching 90-100%. This may be lower for horses receiving intensive treatment.
{{Learning
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[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=%22Colitis+X%22&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&x=39&y=10&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Colitis X publications]
==References==
==References==
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[[Category:Expert_Review]]
[[Category:Expert_Review]]
[[Category:Enteritis,_Bacterial]][[Category:Enteritis,_Fibrinous/Haemorrhagic]]
[[Category:Enteritis,_Bacterial]][[Category:Enteritis,_Fibrinous/Haemorrhagic]]
[[Category:Small Intestinal Diseases - Horse]]
[[Category:Small Intestinal Diseases - Horse]]