Infection with ''H. canis'' is usually non-pathogenic unless animals have had a previous splenectomy or chemotherapy, in these cases the prognosis depends on the severity of clinical signs and level of concurrent disease but treatment is usually successful. | Infection with ''H. canis'' is usually non-pathogenic unless animals have had a previous splenectomy or chemotherapy, in these cases the prognosis depends on the severity of clinical signs and level of concurrent disease but treatment is usually successful. |