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Also known as: '''''Feline Neonatal Isoerythrolysis (FNI) — NI — Equine Neonatal Erythrolysis — ENI
 
Also known as: '''''Feline Neonatal Isoerythrolysis (FNI) — NI — Equine Neonatal Erythrolysis — ENI
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==Description==
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==Introduction==
 
Neonatal isoerythrolysis is a disease of humans and domestic animals and has been most commonly observed in newborn cats and horses. Rarely it has also been described in other species following [[:Category:Transfusion Medicine|blood transfusions]], [[Vaccines|vaccination]] or previous pregnancy. The disease is characterised by [[Immune Mediated Haemolytic Anaemia|immune-mediated haemolytic anaemia]] due to ingestion of maternal colostral antibody directed against surface antigens on neonatal red blood cells. This leads to a [[Type II Hypersensitivity|type II hypersensitivity]] reaction causing extravascular and intravascular haemolysis during the first few days of life.  
 
Neonatal isoerythrolysis is a disease of humans and domestic animals and has been most commonly observed in newborn cats and horses. Rarely it has also been described in other species following [[:Category:Transfusion Medicine|blood transfusions]], [[Vaccines|vaccination]] or previous pregnancy. The disease is characterised by [[Immune Mediated Haemolytic Anaemia|immune-mediated haemolytic anaemia]] due to ingestion of maternal colostral antibody directed against surface antigens on neonatal red blood cells. This leads to a [[Type II Hypersensitivity|type II hypersensitivity]] reaction causing extravascular and intravascular haemolysis during the first few days of life.  
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{{review}}
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[[Category:Materno-Fetal Immunity|E]]
 
[[Category:Materno-Fetal Immunity|E]]
 
[[Category:Immunological Disorders]]
 
[[Category:Immunological Disorders]]
 
[[Category:Immunological Diseases - Horse]][[Category:Immunological Diseases - Cat]]
 
[[Category:Immunological Diseases - Horse]][[Category:Immunological Diseases - Cat]]
 
[[Category:Expert Review]]
 
[[Category:Expert Review]]
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