Pulmonary thromboembolism describes the '''occlusion of pulmonary vessels by a clot'''. It has usually arisen from the systemic venous circulation, embolises to the pulmonary circulation and causes obstruction of the arterial supply to an area of the lung. This results in '''ventilation perfusion mismatch''' occurring where there are areas of the lung which continue to be ventilated but do not receive adequate blood supply. This can result in '''severe hypoxia''' and marked signs of respiratory distress if the area of underperfused but ventilated lung is large. | Pulmonary thromboembolism describes the '''occlusion of pulmonary vessels by a clot'''. It has usually arisen from the systemic venous circulation, embolises to the pulmonary circulation and causes obstruction of the arterial supply to an area of the lung. This results in '''ventilation perfusion mismatch''' occurring where there are areas of the lung which continue to be ventilated but do not receive adequate blood supply. This can result in '''severe hypoxia''' and marked signs of respiratory distress if the area of underperfused but ventilated lung is large. |