This is the residual lumen of '''Rathke's Pouch''' and consists of a series of small cystic cavities (follicles filled with colloid), with both basophillic and chromatophobic (poorly staining) cell types. These extend into the '''pars nervosa'''.T The pars intermedia separates the anterior and posterior lobes. Endocrine cells in this region are known as '''melanotropes'''. These convert the [[Prohormones - Anatomy & Physiology|prohormone]] '''pro-opiomelanocorticotropin''' (POMC) to '''melanocyte stimulating hormone''' (a-MSH) and '''corticotropin-like intermediate lobe peptide''' (CLIP). The pars intermedia is innervated by dopaminergic neurones originating in the periventricular nucleus of the [[Hypothalamus - Anatomy & Physiology|hypothalamus]]. | This is the residual lumen of '''Rathke's Pouch''' and consists of a series of small cystic cavities (follicles filled with colloid), with both basophillic and chromatophobic (poorly staining) cell types. These extend into the '''pars nervosa'''.T The pars intermedia separates the anterior and posterior lobes. Endocrine cells in this region are known as '''melanotropes'''. These convert the [[Prohormones - Anatomy & Physiology|prohormone]] '''pro-opiomelanocorticotropin''' (POMC) to '''melanocyte stimulating hormone''' (a-MSH) and '''corticotropin-like intermediate lobe peptide''' (CLIP). The pars intermedia is innervated by dopaminergic neurones originating in the periventricular nucleus of the [[Hypothalamus - Anatomy & Physiology|hypothalamus]]. |