Changes

*Capsular polysaccharides produced by some strains prevent phagocytosis and interfere with complement

*Capsular polysaccharides produced by some strains prevent phagocytosis and interfere with complement

*Endotoxin is a lipolysaccharide component of the cell wall of Gram-negative bacteria, composed of lipid A, a core polysaccharide and various side chains

*Endotoxin is a lipolysaccharide component of the cell wall of Gram-negative bacteria, composed of lipid A, a core polysaccharide and various side chains

*'''Endotoxin''' is realeased when bacteria die, and causes endothelial damage leading to [[Disseminated Intravascular Coagulation|'''disseminated intravascular coagulation''']] and e'''ndotoxic shock'''; it is also a '''pyrogen'''

*'''Endotoxin''' is realeased when bacteria die, and causes endothelial damage leading to [[Disseminated Intravascular Coagulation|'''disseminated intravascular coagulation''']] and '''endotoxic shock'''; it is also a '''pyrogen'''

*Enterotoxins, verotoxins and cytotoxic necrotising factors produced by many pathogenic ''E. coli''; these produce cell damage at their site of action

*Enterotoxins, verotoxins and cytotoxic necrotising factors produced by many pathogenic ''E. coli''; these produce cell damage at their site of action

*'''Alpha-haemolysin''' may increase iron availability for invading organisms

*'''Alpha-haemolysin''' may increase iron availability for invading organisms

*'''Siderophores''' are made by certain pathogenic strains, and are responsible for iron aquisition; they include aerobactin and enterobactin

*'''Siderophores''' are made by certain pathogenic strains, and are responsible for iron aquisition; they include aerobactin and enterobactin

==Extra-intestinal infection==

==Extra-intestinal infection==