Little is known about he cause of ARVC in cats. In humans and Boxer dogs, ARVC is caused by mutations in various components of the desmosome (necessary for cell-cell adhesion). The resultant loss of mechanical coupling predisposes to arrhythmias. | Little is known about he cause of ARVC in cats. In humans and Boxer dogs, ARVC is caused by mutations in various components of the desmosome (necessary for cell-cell adhesion). The resultant loss of mechanical coupling predisposes to arrhythmias. |