Changes

**Infection may persist with prolonged shedding and clinical relapses

**Infection may persist with prolonged shedding and clinical relapses

**Stress of parturition and lactation may cause shedding of organisms leading to transmission to offspring

**Stress of parturition and lactation may cause shedding of organisms leading to transmission to offspring

*Clinical signs@

*Clinical signs:

**Incubation period 5 days

**Incubation period 5 days

**Conjunctival congestion, clear ocular discharge, blepharospasm

**Conjunctival congestion, clear ocular discharge, blepharospasm

**May have sneezing and nasal discharge

**May have sneezing and nasal discharge

**Resolves within a few weeks, or causes persistent infection

**Resolves within a few weeks, or causes persistent infection

*Diagnosis by antigen detection in ocular/nasal secretions - ELISA, PCR, Kosters, fluorescent antibody test

*Diagnosis:

*Vaccine

 

**Antigen detection in ocular/nasal secretions - ELISA, PCR, Kosters, fluorescent antibody test

 

*Modified live vaccines reduce clinical signs but do not prevent infection or shedding