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**Absorbed toxin affects neuromuscular junction distant from site of toxin production
 
**Absorbed toxin affects neuromuscular junction distant from site of toxin production
 
**Neurotoxin binds irreversibly to ganglioside receptors on motor neurons and is transported to nerve cell body
 
**Neurotoxin binds irreversibly to ganglioside receptors on motor neurons and is transported to nerve cell body
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**Toxins transported to terminals of inhibitory neurons where they block transmission of signals
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**Spastic paralysis results
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**Toxin can be blood-borne and bind to motor terminals throughout the body as well as in the CNS
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*Clinical signs:
 
**
 
**
  
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