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Reproductive Hormones Overview - Anatomy & Physiology (view source)
Revision as of 19:36, 2 November 2013
, 19:36, 2 November 2013→Prostaglandin F2αO
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Oxytocin secretion via the corpus luteum stimulates endometrial production of PGF<sub>2α</sub> and by the end of the luteal phase the concentration of oxytocin and the number of oxytocin recptors within the endometrium allow the production of enough PGF<sub>2α</sub> to breach the threshold level and cause luteolysis. During pregnancy the embryonically produced [[Maternal_Recognition_of_Pregnancy_-_Anatomy_%26_Physiology|pregnancy recognition]] molecules inhibit the secretion of PGF<sub>2α</sub> from the endometrium ensuring that luteolysis cannot occur.
Oxytocin secretion via the corpus luteum stimulates endometrial production of PGF<sub>2α</sub> and by the end of the [[Oestrous_Cycle_-_Anatomy_%26_Physiology|luteal phase]] the concentration of oxytocin and the number of oxytocin recptors within the endometrium allow the production of enough PGF<sub>2α</sub> to breach the threshold level and cause luteolysis. During pregnancy the embryonically produced [[Maternal_Recognition_of_Pregnancy_-_Anatomy_%26_Physiology|pregnancy recognition]] molecules inhibit the secretion of PGF<sub>2α</sub> from the endometrium ensuring that luteolysis cannot occur.
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The ovarian artery is wrapped around the uterine vein. This creates a countercurrent mechanism by which the lipid soluable prostaglandins are able to diffuse from the uterine vein into the [[Ovary_-_Anatomy_%26_Physiology#Arterial_Supply|ovarian artery]]. During the latter stages of the luteal phase as PGF<sub>2α</sub> production increases luteolysis will occur as PGF<sub>2α</sub> Is able to reach its target in the ovary before being metabolized in systemic circulation.
The ovarian artery is wrapped around the uterine vein. This creates a countercurrent mechanism by which the lipid soluable prostaglandins are able to diffuse from the uterine vein into the [[Ovary_-_Anatomy_%26_Physiology#Arterial_Supply|ovarian artery]]. During the latter stages of the [[Oestrous_Cycle_-_Anatomy_%26_Physiology|luteal phase]] as PGF<sub>2α</sub> production increases luteolysis will occur as PGF<sub>2α</sub> Is able to reach its target in the ovary before being metabolized in systemic circulation.
===Prostaglandin (PGE<sub>2</sub>)===
===Prostaglandin (PGE<sub>2</sub>)===