Changes

* '''[[Endocrine_System_-_Pituitary_Gland_-_Anatomy_%26_Physiology#Oxytocin|Oxytocin]]''' is synthesised by magnocellar neurones of the '''Paraventricular nucleus (PVN)''' and '''Supraoptic nucleus (SON)''' of the '''[[Endocrine_System_-_Hypothalamus_-_Anatomy_%26_Physiology#Hypothalamus|Hypothalamus]] '''.

* '''[[Endocrine_System_-_Pituitary_Gland_-_Anatomy_%26_Physiology#Oxytocin|Oxytocin]]''' is synthesised by magnocellar neurones of the '''Paraventricular nucleus (PVN)''' and '''Supraoptic nucleus (SON)''' of the '''[[Endocrine_System_-_Hypothalamus_-_Anatomy_%26_Physiology#Hypothalamus|Hypothalamus]] '''.

* Oxytocin is secreted from the '''[[Endocrine_System_-_Pituitary_Gland_-_Anatomy_%26_Physiology#Posterior_Pituitary_Gland|Posterior Pituitar Gland]]'''.

* Oxytocin is secreted from the '''[[Endocrine_System_-_Pituitary_Gland_-_Anatomy_%26_Physiology#Posterior_Pituitary_Gland|Posterior Pituitar Gland]]'''.

* Plasma oxytocin concentration rises rapidly following suckling stimulation via a '''neuroendocrine reflex''' and exibit '''positive feedback'''.  The positive feedback loop is termenated when stimulation of the teat ceases.

* Plasma oxytocin concentration rises rapidly following suckling stimulation via a '''neuroendocrine reflex''' and exibit '''positive feedback'''.  The positive feedback loop is terminated when stimulation of the teat ceases.

'''Afferent pathway''': Mechanical stimulation of the teats activates pressure sensitive receptors in the dermis where the pressure is transformed into nerve impulses that travel via the spinothalamic nerve tract to the brain. These nerves synapse in the PVN and SON. When the cell bodies of the oxytocin-containing neurons are stimulated by these impulses originating in the teat, an action potential moves down the oxytocin-containing neurons from the cell body in the hypothalamus down the axon to the neuron ending in the posterior pituitary. This causes release of oxytocin and neurophysin into the blood.  

'''Afferent pathway''': Mechanical stimulation of the teats activates pressure sensitive receptors in the dermis where the pressure is transformed into nerve impulses that travel via the spinothalamic nerve tract to the brain. These nerves synapse in the PVN and SON. When the cell bodies of the oxytocin-containing neurons are stimulated by these impulses originating in the teat, an action potential moves down the oxytocin-containing neurons from the cell body in the hypothalamus down the axon to the neuron ending in the posterior pituitary. This causes release of oxytocin and neurophysin into the blood.