| Many products aimed at improving cognitive function of older animals are mixtures of multiple ingredients such as antioxidants, mitochondrial cofactors, fatty acids (especially polyunsaturated fatty acids - omega 3 and 6 oils) amongst others which are generally thought to have a positive effect on the development of cognitive dysfunction. Additional ingredients which may be found in a supplement or diet with the aim of slowing cognitive dysfunction include vitamins C, E and B<sub>6</sub>, choline, phosphatidylcholine, alpha-lipoid acid, resveratrol, gingkobiloba, carnitine and flavonoids and carotenoids. | | Many products aimed at improving cognitive function of older animals are mixtures of multiple ingredients such as antioxidants, mitochondrial cofactors, fatty acids (especially polyunsaturated fatty acids - omega 3 and 6 oils) amongst others which are generally thought to have a positive effect on the development of cognitive dysfunction. Additional ingredients which may be found in a supplement or diet with the aim of slowing cognitive dysfunction include vitamins C, E and B<sub>6</sub>, choline, phosphatidylcholine, alpha-lipoid acid, resveratrol, gingkobiloba, carnitine and flavonoids and carotenoids. |
− | Products which are more specific and focus on an active ingredient include those with S-adenosyl-L-methionine (SAMe) which is thought to improve depression in humans<ref>Papakostas, G.I. The use of complementary and alternative medicines to achieve remission in major depressive disorder. J Clin Psychiatry 2009;70(Suppl. 5):18-22.</ref> and apoaequorin. Care should be taken when using SAMe in conjunction with behavioural drugs such as [[Clomipramine|clomipramine]] a tricyclic antidepressant (TCA) and [[Fluoxetine|fluoxetine]] a selective serotonin re-uptake inhibitor (SSRI) as it may augment serotonin levels and therefore potentially cause toxicity due to serotonin syndrome. | + | Products which are more specific and focus on an active ingredient include those with S-adenosyl-L-methionine (SAMe) which is thought to improve depression in humans<ref>Papakostas, G.I. The use of complementary and alternative medicines to achieve remission in major depressive disorder. J Clin Psychiatry 2009;70(Suppl. 5):18-22.</ref> and apoaequorin. Care should be taken when using SAMe in conjunction with behavioural drugs such as [[Clomipramine|clomipramine]] a tricyclic antidepressant (TCA) and [[Fluoxetine|fluoxetine]] a selective serotonin re-uptake inhibitor (SSRI) as it may augment serotonin levels and therefore potentially cause toxicity resulting in serotonin syndrome. |