Changes

|Stimulates digestion of fat and protein by causing release of digestive enzymes and bile from the pancreas and gall bladder.

|Stimulates digestion of fat and protein by causing release of digestive enzymes and bile from the pancreas and gall bladder.

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|Gastrin

|<font color=red>Gastrin</font>

|G-Cells in Stomach and duodenum

|G-Cells in Stomach and duodenum

|Stimulates Parietal cells in the stomach to secrete HCl and Chief cells to secrete pepsinogen.

|Stimulates Parietal cells in the stomach to secrete HCl and Chief cells to secrete pepsinogen.

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|Gastric Inhibitory Peptide

|<font color=red>Gastric Inhibitory Peptide</font>

|Duodenum and Jejunum  

|Duodenum and Jejunum  

|Inhibits gastric motility and HCl secretion in the stomach, induces insulin secretion.

|Inhibits gastric motility and HCl secretion in the stomach, induces insulin secretion.

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|Ghrelin

|<font color=red>Ghrelin</font>

|Stomach and Pancreas

|Stomach and Pancreas

|Increases food intake (by stimulating hunger) at the level of the hypothalamus

|Increases food intake (by stimulating hunger) at the level of the hypothalamus

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|Secretin

|<font color=red>Secretin</font>

|Crypts of Leiberkuhn in the Duodenum  

|Crypts of Leiberkuhn in the Duodenum  

|Causes secretion of bicarbonate to buffer the pH of the chyme entering the small intestine. Also triggers insulin release.

|Causes secretion of bicarbonate to buffer the pH of the chyme entering the small intestine. Also triggers insulin release.

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|Somatostatin  

|<font color=red>Somatostatin </font>

|Gastric glands of the stomach

|Gastric glands of the stomach

|Inhibits release of gastrin and HCl from the stomach, inhibits secretin and cholecystokinin release from the duodenum and inhibits release of glucagon from the pancreas.

|Inhibits release of gastrin and HCl from the stomach, inhibits secretin and cholecystokinin release from the duodenum and inhibits release of glucagon from the pancreas.

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