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| * The foetus receives its genetic endowment in two equal portions from the male gamete ('''Spermatozoon''') and female gamete ('''Oocyte'''). | | * The foetus receives its genetic endowment in two equal portions from the male gamete ('''Spermatozoon''') and female gamete ('''Oocyte'''). |
| * The X sex chromosome is larger than the Y sex chromosome. | | * The X sex chromosome is larger than the Y sex chromosome. |
− | * '''Females''' have XX chromosomes. All oocytes contain one X chromosome, they are the '''homogametic''' sex. | + | * '''Females''' have '''XX''' chromosomes. All oocytes contain one X chromosome, they are the '''homogametic''' sex. |
− | * '''Males''' have XY chromosomes. Spermatozoa form two distinct populations, one containing X chromosomes and one containing Y chromosomes. They are the '''heterogametic''' sex. | + | * '''Males''' have '''XY''' chromosomes. Spermatozoa form two distinct populations, one containing X chromosomes and one containing Y chromosomes. They are the '''heterogametic''' sex. |
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| * The '''Y''' chromosome is required to '''initiate male development'''. | | * The '''Y''' chromosome is required to '''initiate male development'''. |
| * In absence of the Y chromosome, female gonads (Ovaries) will develop. | | * In absence of the Y chromosome, female gonads (Ovaries) will develop. |
− | * The prime male determining gene is '''SRY''' (sex determining region of the Y chromosome). SRY is a very small piece of DNA that acts as a molecular switch to regulate structural genes and autosomal chromosomes | + | * The prime male determining gene is '''SRY''' (sex determining region of the Y chromosome). * SRY is a very small piece of DNA that acts as a molecular switch to regulate structural genes and autosomal chromosomes, determining if and when they are to be activated. |
| * The presence of SRY alone is sufficient to ensure development of male gonads (Testes). | | * The presence of SRY alone is sufficient to ensure development of male gonads (Testes). |
| + | * Female is the default sex, in absence of SRY female gonads (Ovaries) will develop. |
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| + | * Subsequent gonadal development is dependent on a normal population of '''germ cells'''. |
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| == Internal Genetalia == | | == Internal Genetalia == |