Changes

Jump to navigation Jump to search
New page: '''''Aetiology''''' * Genotype is XX as should be female * Ovaries develop normally * Foetal Adrenal Gland is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''2...
'''''Aetiology'''''

* Genotype is XX as should be female
* Ovaries develop normally
* Foetal Adrenal Gland is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''21 hydroxylase mutation'''.



'''''Consequence'''''

* Wolffian Ducts persist due to the presence of Androgens, thus allowing development of '''male internal and external genitalia'''.
* Mullarian Ducts persist due to the absence of testes, hence absence of Sertoli cell MIH secretion. This allows formation of '''female internal genitalia'''.



'''''Morphology'''''

* Appears male with a '''micropenis and scrotum'''
* Both male and female internal genitalia
4,503

edits

Navigation menu