Author, Donkey, Bureaucrats, Administrators
53,803
edits
Changes
Jump to navigation
Jump to search
no edit summary
==Squamous Cell Carcinoma (SCC)==
==Squamous Cell Carcinoma (SCC)==
In a survey of dogs with oropharyngeal tumors, SCC was the second most frequently diagnosed oral tumor (24.5 %), and sites of involvement included gingiva, tonsil, oral mucosa, lip and palate. In two surveys of oropharyngeal tumors in cats the most frequently diagnosed tumor was SCC, representing 61–64% of the oral tumors.
In a survey of dogs with oropharyngeal tumors, [[Squamous Cell Carcinoma|SCC]] was the second most frequently diagnosed oral tumor (24.5 %), and sites of involvement included gingiva, tonsil, oral mucosa, lip and palate. In two surveys of oropharyngeal tumors in cats the most frequently diagnosed tumor was SCC, representing 61–64% of the oral tumors.
The mean age of dogs with gingival SCC was 8.4 years; no sex or breed predilection was noted. The tumors were described as typically reddened, friable and vascular. The clinical history frequently included tooth extraction with subsequent tumor growth at the extraction site.
The mean age of dogs with gingival SCC was 8.4 years; no sex or breed predilection was noted. The tumors were described as typically reddened, friable and vascular. The clinical history frequently included tooth extraction with subsequent tumor growth at the extraction site.
==Malignant Melanoma (MM)==
==Malignant Melanoma (MM)==
Malignant melanoma is the most common malignant oral tumor in dogs. Males are predisposed, with a male to female ratio of 3 : 1 to 6 : 1, and mean age of 10.5–12 years. The majority of MM involve the gingiva. Other sites of involvement include the labial mucosa, palate, buccal mucosa and tongue. Melanomas are uncommon in cats, with ocular and cutaneous sites more common than the oral cavity. Melanomas of the lip that arise from mucous membranes typically have a better prognosis than gingival tumors but are more aggressive than tumors arising from haired skin.
Malignant [[melanoma]] is the most common malignant oral tumor in dogs. Males are predisposed, with a male to female ratio of 3 : 1 to 6 : 1, and mean age of 10.5–12 years. The majority of MM involve the gingiva. Other sites of involvement include the labial mucosa, palate, buccal mucosa and tongue. Melanomas are uncommon in cats, with ocular and cutaneous sites more common than the oral cavity. Melanomas of the lip that arise from mucous membranes typically have a better prognosis than gingival tumors but are more aggressive than tumors arising from haired skin.
Melanomas are firm, greyish or brownish black, rapidly enlarge, develop ulceration, hemorrhage and metastasis within weeks or months.
Melanomas are firm, greyish or brownish black, rapidly enlarge, develop ulceration, hemorrhage and metastasis within weeks or months.
==Fibrosarcoma (FS)==
==Fibrosarcoma (FS)==
The third most common tumor in dogs was FS representing 17.7% of oral tumors. In tumors in cats, FS represented the second most common oral tumor representing 12.9% and 22.0% of the oral tumors in two surveys.
The third most common tumor in dogs was [[fibrosarcoma]] representing 17.7% of oral tumors. In tumors in cats, FS represented the second most common oral tumor representing 12.9% and 22.0% of the oral tumors in two surveys.
Surgery alone for oral FS results in a relatively high local recurrence rate. A histologically low-grade yet biologically high-grade FS of the mandible and maxilla is a distinct histopathologic entity that has been identified in dogs. The histopathologic appearance is compatible with benign fibrous connective tissue but the biologic behavior indicates otherwise, with 72.7% of dogs evaluated found to have underlying bone lysis. Additionally, 12.0% ultimately developed pulmonary metastasis and 20.0% regional lymph node metastasis. The most common breed affected appears to be Golden Retrievers.
Surgery alone for oral FS results in a relatively high local recurrence rate. A histologically low-grade yet biologically high-grade FS of the mandible and maxilla is a distinct histopathologic entity that has been identified in dogs. The histopathologic appearance is compatible with benign fibrous connective tissue but the biologic behavior indicates otherwise, with 72.7% of dogs evaluated found to have underlying bone lysis. Additionally, 12.0% ultimately developed pulmonary metastasis and 20.0% regional lymph node metastasis. The most common breed affected appears to be Golden Retrievers.