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Sexual Differentiation - Anatomy & Physiology (view source)
Revision as of 13:29, 3 July 2008
, 13:29, 3 July 2008→Sexual Differentiation of the Brain
== Sexual Differentiation of the Brain ==
== Sexual Differentiation of the Brain ==
'''MALE'''
* '''Testosterone''' secreted into the blood reaches the brain.
* Converted to Dehydrotestosterone and '''Oestradiol''' by Aromatase enzymes in the Hypothalamus.
* Oestradiol masculinises the brain
'''FEMALE'''
* '''Alpha Fetoprotein''' binds Oestradiol, preventing it from crossing the blood-brain barrier.
* Oestradiol cannot access the Hypothalamus
* Protects female brain from masculising effects of Oestradiol.
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