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| | {| border="1" cellpadding="5" cellspacing="0" | | {| border="1" cellpadding="5" cellspacing="0" |
| − | |+ ''Liver'' | + | |+ ''Liver hormones'' |
| | !Hormone | | !Hormone |
| | !Regulation and Production | | !Regulation and Production |
| | !Action | | !Action |
| | |- | | |- |
| − | |<font color=Purple>Leptin</font> | + | |<font color=Purple>Insulin-Like Growth Factor 1 (IGF-1)</font> |
| − | |Leptin is produced when the body has had adequate to eat. | + | |[[Endocrine System - Pituitary Growth Hormone - Anatomy & Physiology|Growth Hormone]] released from the pituitary gland binds to receptors on liver cells which causes them to synthesise and secrete IGF-1. |
| − | |Sends a signal to the ''appetite centre'' of the [[Endocrine System - Hypothalamus - Anatomy & Physiology|Hypothalamus]] indicating satiety. Leptin also seems to be a significant regulator of reproductive function, as animals with low body mass, and thus low leptin levels fail to cycle.
| + | |IGF-1 has insulin-like effects as it can bind to the Insulin Receptor, and is also the stimulus for growth in the body. Almost all cell types respond to IGF-1. |
| | |- | | |- |
| − | |<font color=Purple>Resistin</font> | + | |<font color=Purple>Angiotensinogen</font> |
| − | | - | + | |Angiotensinogen is the precursor to angiotensin 1, and is part of the [[Renin-Angiotensin-Aldosterone System (RAAS) - Anatomy & Physiology|Renin-Angiotensin-Aldosterone system]]. |
| − | |Participates in the [[General Pathology - Basic Aspects of the Immune Response|immune response.]] It may have some role in obesity and Type II Diabetes mellitus. | + | |Is converted to Angiotensin by [[Endocrine System - Kidney - Anatomy & Physiology|renin]] which in turn is converted to other substrates which act to raise blood pressure during hypotension. |
| | + | |- |
| | + | |<font color=Purple> [[Thrombopoiesis - Anatomy & Physiology#Thrombopoeitin|Thrombopoeitin]]</font> |
| | + | | |
| | + | |Causes bone marrow precursor cells to develop into [[Thrombopoiesis - Anatomy & Physiology#Megakaryocyte|Megakaryocyte]], platelet precursors. |
| | |} | | |} |