Changes

Interferons are [[cytokines]] that have '''anti-viral, antiproliferative and immunomodulatory effects'''. Virbagen®Omega is a recombinant omega interferon of feline origin (rFeIFN- ω) produced by genetic engineering. Virbagen®Omega is a Type 1 Interferon, closely related to human alpha and beta interferons. [[Interferons]] bind to specific receptors on the plasma membrane of other cells. The binding activates a complex transcriptional cascade, leading to the up-regulation of more than 20 cellular genes, producing an interferon-activated cell. IFN-induced proteins are numerous and each protein confers a new property to the cell.  This may be antiviral, immune modulating or antiproliferative. The antiviral effect of an interferon-activated cell results from the induction of specific proteins which inhibit viral multiplication and viral protein synthesis. The antiproliferative effect of an interferon-activated cell results in regulation of the genes controlling cell division which can lead to the inhibition of cell proliferation and an anti-tumoral effect.<br><br>

Interferons are [[cytokines]] that have '''anti-viral, antiproliferative and immunomodulatory effects'''. Virbagen®Omega is a recombinant omega interferon of feline origin (rFeIFN- ω) produced by genetic engineering. Virbagen®Omega is a Type 1 Interferon, closely related to human alpha and beta interferons. [[Interferons]] bind to specific receptors on the plasma membrane of other cells. The binding activates a complex transcriptional cascade, leading to the up-regulation of more than 20 cellular genes, producing an interferon-activated cell. IFN-induced proteins are numerous and each protein confers a new property to the cell.  This may be antiviral, immune modulating or antiproliferative. The antiviral effect of an interferon-activated cell results from the induction of specific proteins which inhibit viral multiplication and viral protein synthesis. The antiproliferative effect of an interferon-activated cell results in regulation of the genes controlling cell division which can lead to the inhibition of cell proliferation and an anti-tumoral effect.<br><br>

The benefits of using Interferon in feline chronic gingivostomatitis (FCGS) have yet to be properly documented and studied but consensus in practice is that there are significant benefits. Interferon is recommended as an adjunct to the other treatments. Initially systemic administration followed by daily oral dosage was used. However, the current recommendation is to use intralesional injections at the time of main treatment, followed by oral dosage.  

The benefits of using Interferon in feline chronic gingivostomatitis (FCGS) have yet to be properly documented and studied but consensus in practice is that there are significant benefits. Interferon is recommended as an adjunct to the other treatments. Initially systemic administration followed by daily oral dosage was used. However, the current recommendation is to use intralesional injections at the time of main treatment, followed by oral dosage.  

[[Category:Dental and Oral Medication]]

[[Category:Dental and Oral Medication]]

[[Category:Waltham reviewed]]

[[Category:Waltham reviewed]]