Changes

===Dog:===  

===Dog:===  

There is a considerable amount of information on the susceptibility of certain breeds to copper hepatopathy. The disease is predominantly associated with Bedlington terriers but breeds such as the Labrador retriever, West Highland white terrier, Skye terrier and Dobermann pinscher have also been reported to be prone to this condition, which is caused by an inherited defect that results in toxic excesses of copper in the liver, causing hepatitis and cirrhosis. Affected dogs can have liver copper concentrations ten times normal values. The condition is due to a defect in the biliary excretion of copper, which is the main control of copper balance<ref>Brewer, G (1998). “Wilson’s disease and canine copper toxicosis”. Am. J. Clin. Nutr. 67(suppl.):1087S-1090S.</ref>. Treatment is via zinc supplementation, which reduces copper absorption <span style="color:red">[WikiVet Link to Zinc]</span>, or chelating agents that increase copper excretion<ref>Hyun, C, Filippich, LJ (2004). “Inherited copper toxicosis with emphasis on toxicosis in Bedlington terriers”. J. Exp. Anim. Sci. 43:39-64.</ref>.  

There is a considerable amount of information on the susceptibility of certain breeds to copper hepatopathy. The disease is predominantly associated with Bedlington terriers but breeds such as the Labrador retriever, West Highland white terrier, Skye terrier and Dobermann pinscher have also been reported to be prone to this condition, which is caused by an inherited defect that results in toxic excesses of copper in the liver, causing hepatitis and cirrhosis. Affected dogs can have liver copper concentrations ten times normal values. The condition is due to a defect in the biliary excretion of copper, which is the main control of copper balance<ref>Brewer, G (1998). “Wilson’s disease and canine copper toxicosis”. Am. J. Clin. Nutr. 67(suppl.):1087S-1090S.</ref>. Treatment is via [[Zinc - Nutrition|zinc]] supplementation, which reduces copper absorption, or chelating agents that increase copper excretion<ref>Hyun, C, Filippich, LJ (2004). “Inherited copper toxicosis with emphasis on toxicosis in Bedlington terriers”. J. Exp. Anim. Sci. 43:39-64.</ref>.

===Cat:===   

===Cat:===