| All body tissues have a requirement for glucose and it must be obtained regularly from either the diet or synthesised through hepatic gluconeogenesis. | | All body tissues have a requirement for glucose and it must be obtained regularly from either the diet or synthesised through hepatic gluconeogenesis. |
− | Once absorbed through the intestinal epithelium, glucose enters the portal circulation and can be undergo intercellular transport for intermediate metabolism and formation of ATP. Glucose, galactose and fructose can also be used to synthesise additional molecules, such as glycogen and fatty acid<ref name="Ebiner"/><ref name="Flatt"/>. In the absence of dietary starches and sugar, or during periods of starvation, hepatic gluconeogenesis can support maintenance of normal blood glucose concentrations in adult animals as long as adequate amounts of gluconeogenic amino acids are present<ref name="Romsos">Romsos DR, et al. Influence of low carbohydrate diet on performance of pregnant and lactating dogs. J Nutr 1981;111:678-689.</ref>. | + | Once absorbed through the intestinal epithelium, glucose enters the portal circulation and can be undergo intercellular transport for intermediate metabolism and formation of ATP. Glucose, galactose and fructose can also be used to synthesise additional molecules, such as glycogen and fatty acid<ref name="Ebiner"/><ref name="Flatt"/>. In the absence of dietary starches and sugar, or during periods of starvation, hepatic gluconeogenesis can support maintenance of normal blood glucose concentrations in adult animals as long as adequate amounts of gluconeogenic [[Amino Acids Overview - Nutrition|amino acids]] are present<ref name="Romsos">Romsos DR, et al. Influence of low carbohydrate diet on performance of pregnant and lactating dogs. J Nutr 1981;111:678-689.</ref>. |