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Sexual Differentiation - Anatomy & Physiology (view source)
Revision as of 08:38, 8 July 2008
, 08:38, 8 July 2008no edit summary
* At this stage it is not possible to discriminate between male and female gonads.
* At this stage it is not possible to discriminate between male and female gonads.
* Y chromosomal determination of gonadal sex is only visible when primordial germ cell colonisation is complete.
* Y chromosomal determination of gonadal sex is only visible when primordial germ cell colonisation is complete.
* '''Between cords''', the loose mesenchyme undergoes '''vascularisation''' and develops as '''stromal tissue'''.
* '''Between cords''', the loose mesenchyme undergoes '''vascularisation''' and develops as '''stromal tissue'''.
* Within the stromal tissue, cells condense into clusters to form specialized endocrine units - the interstitial '''Leydig Cells'''
* Within the stromal tissue, cells condense into clusters to form specialized endocrine units - the interstitial '''Leydig Cells'''
** '''Mesenchymal cells''' give rise to '''Granulosa cells'''
** '''Mesenchymal cells''' give rise to '''Granulosa cells'''
** '''Germ cells''' give rise to '''Oocytes'''
** '''Germ cells''' give rise to '''Oocytes'''
** Cranial Vagina
** Cranial Vagina
* Normal Ovarian activity is NOT essential for the development of normal female internal genetalia.
* Normal Ovarian activity is NOT essential for the development of normal female internal genetalia.
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* Failure of proper endocrine communication between the gonads, internal and external genitalia can lead to '''dissociation''' of gonadal and genital sex.
* Failure of proper endocrine communication between the gonads, internal and external genitalia can lead to '''dissociation''' of gonadal and genital sex.
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== Sexual Differentiation of the Brain ==
== Sexual Differentiation of the Brain ==